I am in a meeting so I will not be able to read your mail the next 2 hours. This is an example of time consuming information overload, probably with the best intentions. But I am not interested in spending time on reading that you're not available. Instead write me when you are, and if I really want to know what you are doing, write it on twitter, jaiku, facebook etc. I believe that its time to declare the out of office reply for dead. Its time to give information quality not quantity. And if everything goes wrong I bet you still have a phone. So next time you receive an "out of office reply" bend your head and have 1 minutes peace. So the next time I get a reply I will feel excited when I am reading your answer, instead of the disappointment of time loss.